Fluid flow

A conceptual framework for analysing the energetics of density-stratified Boussinesq fluid flows is discussed. The concept of gravitational available potential energy is used to formulate an energy budget in which the evolution of the background potential energy, i.e. the minimum potential energy attainable through adiabatic motions, can be explicitly examined. For closed systems, the background potential energy can change only due to diabatic processes. The rate of change of background potential energy is proportional to the molecular diffusivity. Changes in the background potential energy provide a direct measure of the potential energy changes due to irreversible diapycnal mixing. For open systems, background potential energy can also change due to boundary fluxes, which can be explicitly measured. The analysis is particularly appropriate for evaluation of diabatic mixing rates in numerical simulations of turbulent flows. The energetics of a shear driven mixing layer is used to i...

This paper presents current knowledge about the structure and function of the lymphatic system. Mathematical models of lymph flow in the single lymphangion, the series of lymphangions, the lymph nodes, and the whole lymphatic system are considered. The main results and further perspectives are discussed.

A numerical study has been conducted to investigate the fluid flow and heat transfer of an air-cooled metal foam heat exchanger under the high speed laminar jet confined by two parallel walls for which the range of the Reynolds number is 600–1000. Two independent numerical solvers were used and cross-validated being a FORTRAN code and the commercially available software CFD-ACE. The effects of local thermal non-equilibrium, thermal dispersion, porosity, and pore density on the heat transfer augmentation are examined for different Reynolds numbers. Application of energy flux vectors, for convection visualization, is also illustrated for a more comprehensive analysis of the problem. Finally, the performance of the metal foam heat exchanger is compared to that of conventional finned design. It is observed that the heat removal rate can be greatly improved at almost no excess cost.

Summary Simplified 2 D finite element fracture models have been presented in this paper. The model handles matrix-fracture, fracture- fracture, and matrix-matrix connections. Finite element method is used for 2 D single-phase flow in fractured porous medium. We have modeled horizontal and vertical fractures through porous and less permeable medium. We have also modeled fractures intersected at a right angle.

In this paper, we present design of a transdermal drug delivery system for treatment of cardiovascular or hemodynamic disorders such as hypertension. The system comprises of integrated control electronics and microelectromechanical system devices such as micropump, micro blood pressure sensor and microneedle array. The objective is to overcome the limitations of oral therapy such as variable absorption profile and the need for frequent dosing, by fabricating a safe, reliable and cost effective transdermal drug delivery system to dispense various pharmacological agents through the skin for treatment of hemodynamic dysfunction such as hypertension. Moreover, design optimization of a piezoelectrically actuated valveless micropump is presented for the drug delivery system. Because of the complexity in analysis of piezoelectric micropump, which involves structural and fluid field couplings in a complicated geometrical arrangement, finite element (FE) numerical simulation rather than an analytical system has been used. The behavior of the piezoelectric actuator with biocompatible polydimethylsiloxane membrane is first studied by conducting piezoelectric analysis. Then the performance of the valveless micropump is analyzed by building a three dimensional electric-solid-fluid model of the micropump. The effect of geometrical dimensions on micropump characteristics and efficiency of nozzle/diffuser elements of a valveless micropump is investigated in the transient analysis using multiple code coupling method. The deformation results of the membrane using multifield code coupling analysis are in good agreement with analytical as well as results of single code coupling analysis of a piezoelectric micropump. The analysis predicts that to enhance the performance of the micropump, diffuser geometrical dimensions such as diffuser length, diffuser neck width and diffuser angle need to be optimized. Micropump flow rate is not strongly affected at low excitation frequencies from 10 to 200 Hz. The excitation voltage is the more dominant factor that affects the flow rate of the micropump as compared with the excitation frequency. However, at extremely high excitation frequencies beyond 8,000 Hz, the flow rate drops as the membrane exhibits multiple bending peaks which is not desirable for fluid flow. Following the extensive numerical analysis, actual fabrication and performance characterization of the micropump is presented. The performance of the micropump is characterized in terms of piezoelectric actuator deflection and micropump flow rate at different operational parameters. The set of multifield simulations and experimental measurement of deflection and flow rate at varying voltage and excitation frequency is a significant advance in the study of the electric-solid-fluid coupled field effects as it allows transient, three dimensional piezoelectric and fluid analysis of the micropump thereby facilitating a more realistic multifield analysis. The results of the present study will also help to conduct relevant strength duration tests of integrated drug delivery device with micropump and microneedle array in future.

SUMMARY Numerical simulations of long-term crustal deformation reveal the important role that damage healing (ie fault-zone strengthening) plays in the structural evolution of strike-slip fault systems. We explore the sensitivity of simulated fault zone structure and evolution patterns to reasonable variations in the healing-rate parameters in a continuum damage rheology model. Healing effectiveness, defined herein as a function of the healing rate parameters, describes the post-seismic healing process in terms of the characteristic inter- ...

A new methodology,for interactive design of turbomachinery blades ispresented. Software implementation,of the methods,provides a user interface that is intuitive to aero-designers while ,operating with stan- dardized geometric forms. The primary contribution is that blade sec- tions may ,be defined ,with respect to general ,surfaces of revolution which may ,be defined ,to represent the path of fluid flow through the