Single Cell

The distributions of the times to turbidity for wells inoculated with single cells of Listeria innocua were determined in different environmental conditions (pH 4.5 to 7 and with 0.5% to 8% of NaCl at 30 degrees C). It was established by statistical analysis that the main source of the variability of the detection times, T, is the variability of individual lag times. A linear relation dev(T) approximately T was observed between the detection times and their standard deviation. At slow growth, other sources of variability became increasingly significant.

We present a novel microwell array platform suited for various cell-imaging assays where single cell resolution is important. The platform consists of an exchangeable silicon-glass microchip for cell biological applications and a custom made holder that fits in conventional ...

Our effort towards the attainment of high performance devices has yielded several devices with total-area conversion efficiencies above 16%, the highest measuring 16.8% under standard reporting conditions (ASTM E892-87, Global 1000 W/m2). The first attempts to translate this development to larger areas resulted in an efficiency of 12.5% for a 16.8-cm2 monolithically interconnected submodule test structure, and 15.3% for a 4.85-cm2 single cell. Achievement of a 17.2% device efficiency fabricated for operation under concentration (22-sun) is also reported. All high efficiency devices reported here are made from graded bandgap absorbers. Bandgap grading is achieved by compositional Ga/(In+Ga) profiling as a function of depth. The fabrication schemes to achieve the graded absorbers, the window materials and contacting are described

The preparation of single-cell suspensions from tissues is an important prerequisite for many experiments in cellular research. The process of dissociating whole organs requires specific parameters in order to obtain a high number of viable cells in a reproducible manner. The gentleMACS Dissociator optimizes this task with a simple, practical protocol. The instrument contains pre-programmed settings that are optimized for the efficient but gentle dissociation of a variety of tissue types, including mouse lungs. In this publication the use of the gentleMACS Dissociator on lung tissue derived from mice is demonstrated.

In this paper, we propose and analyse the model of competition between a single cell cancer and the immune system. The model is a system of integro-differential bilinear equations and it describes both very early stage of a solid tumor and all stages of leukemias.

1. INTRODUCTION p53 is a transcription factor that regulates cell cycle and functions as a tumor supressor. The concentration of p53 increases in response to stress signal, such as DNA damage or oncogene activation. p53 induces transcription of several hundred genes ...